Chemicals found in grape seeds significantly inhibited growth of colorectal tumors in both cells cultures and in mice, according to researchers who have already demonstrated the extracts anti- cancer effects in other tumor types.
Their study published in the October 18 issue of Clinical Cancer Research, documented a 44 percent reduction of advanced colorectal tumors in the animals, and also revealed, for the first time, the molecular mechanism by which grape seed extract work to inhibit cancer growth. The authors found that it increases availability of critical protein, Cip1/p21, in tumors that effectively freezes the cell cycle, and often pushes a cancer cell to self destruct.
"With these results, we are not suggesting that people run out and buy and use grape seed extract. That could be dangerous since so little is known about doses and side effects." Said Rajesh Agarwal, Ph.D., professor in the Department of Pharmaceutical Sciences at the University of Colorado Health Sciences Center in Denver.
"The value of this preclinical study is that it shows grape seed extract can attack cancer and how it works, but much more investigation will be needed before these chemicals can be tested as a human cancer treatment and preventive," he said.
***Grape seeds are high in proanthocyanins which are included ingredients in many of the FTH and Montiff formulations.
***BeautynHealth.com provides the above amino acids, vitamins and antioxidants produced by FTH and Montiff Nutraceutical companies and Coral Inc. FTH L Tryptophan has been shown to be helpful for inducing sleep and relaxation. The purity of these brands greatly surpasses the minimum requirements for USP (United States Pharmacopeia), JP (Japanese Pharmacopeia) and EP (European Pharmacopeia).